Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001362 | 0.83 | KMT2A (0.48) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7666397 | 0.82 | KMT2A (0.40) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7661646 | 0.78 | TLR7 (0.41) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7671571 | 0.77 | TLR7 (0.45) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7656794 | 0.76 | PDE4B (0.40) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6999063 | 0.74 | KMT2A (0.48) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7003070 | 0.74 | PDE5A (0.48) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6996208 | 0.73 | PDE5A (0.47) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6996654 | 0.73 | KMT2A (0.46) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7003426 | 0.72 | KMT2A (0.46) | KMT2AADORA3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880524-A1 | NEW TRIAZOLOPURINES, METHOD OF PREPARING THEM AND THEIR USE AS DRUGS | Boehringer Ingelheim Pharma KG (DE) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998003511-A1 | NEW TRIAZOLOPURINES, METHOD OF PREPARING THEM AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1998-01-29 | — | — | WO | disclosed |