Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | GGT1 | P19440 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557661 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSLC40A1PTGDR2GGT1 | |
| SCHEMBL8557951 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPTSLC40A1GGT1MAPK1 | |
| SCHEMBL8556318 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTSLC40A1PTGDR2GGT1 | |
| SCHEMBL8554218 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTSLC40A1PTGDR2GGT1 | |
| SCHEMBL9026442 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MAPTSLC40A1GGT1MAPK1 | |
| SCHEMBL8553427 | 0.85 | PIK3CD (0.48) | ALDH1A1MAPTSLC40A1PTGDR2GGT1 | |
| SCHEMBL8553397 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTSLC40A1GGT1RAB9A | |
| SCHEMBL8559957 | 0.84 | MAPT (0.47) | ALDH1A1MAPTSLC40A1MAPK1L3MBTL1 | |
| SCHEMBL8556290 | 0.84 | MAPT (0.51) | ALDH1A1MAPTSLC40A1PTGDR2GGT1 | |
| SCHEMBL8556104 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPTSLC40A1GGT1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |