Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9026442 | 0.92 | ALDH1A1 (0.46) | ALDH1A1KMT2AGGT1MAPTLMNA | |
| SCHEMBL8556104 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KMT2AGGT1MAPTLMNA | |
| SCHEMBL8556764 | 0.89 | MAPT (0.54) | ALDH1A1KMT2AMAPTLMNACYP2C9 | |
| SCHEMBL8556290 | 0.89 | MAPT (0.51) | ALDH1A1GGT1MAPTLMNATP53 | |
| SCHEMBL8560530 | 0.88 | MAPT (0.52) | ALDH1A1KMT2AMAPTLMNACYP3A4 | |
| SCHEMBL8559957 | 0.86 | MAPT (0.47) | ALDH1A1KMT2AMAPTLMNATP53 | |
| SCHEMBL8555221 | 0.85 | MAPT (0.56) | ALDH1A1KMT2AMAPTLMNAPTPN2 | |
| SCHEMBL8557761 | 0.85 | MAPT (0.49) | ALDH1A1KMT2AMAPTLMNAPTPN2 | |
| SCHEMBL8560689 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2AGGT1MAPTLMNA | |
| SCHEMBL8557661 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GGT1MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |