Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 7/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373697 | 0.72 | ESR2 (0.83) | ESR1ESR2HDAC6ABHD6CA1 | |
| SCHEMBL566629 | 0.71 | ESR1 (0.58) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL2585109 | 0.71 | ESR1 (0.62) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL373718 | 0.71 | ESR1 (0.58) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL7849236 | 0.71 | ESR2 (0.58) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL1787936 | 0.71 | ABHD6 (0.60) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL27176737 | 0.71 | ESR1 (0.58) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL1791230 | 0.70 | ESR1 (0.55) | ESR1ESR2HDAC6PKM | |
| SCHEMBL7423258 | 0.70 | ESR1 (0.57) | ESR1ESR2HDAC6PKMABHD6 | |
| SCHEMBL506139 | 0.70 | ESR1 (0.59) | ESR1ESR2ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |