Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412249 | 0.86 | KDM4E (0.59) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL23413027 | 0.86 | KDM4E (0.59) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL8564487 | 0.85 | CYP1A2 (0.50) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL8566047 | 0.85 | TLR8 (0.54) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL16836341 | 0.83 | RAB9A (0.57) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL13533394 | 0.82 | TLR8 (0.58) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL16836548 | 0.82 | TLR8 (0.56) | TSHRCYP1A2KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL29935791 | 0.81 | PDGFRB (0.49) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL30898597 | 0.81 | RAB9A (0.50) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB | |
| SCHEMBL29248551 | 0.81 | RAB9A (0.50) | CYP1A2KDM4ESMN1; SMN2KMT2APDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958918-B | Novel tobacco amide derivatives or its salt | FUJIFILM CORP. (JP) | 2015-12-09 | — | — | CN | disclosed |
| CN-103492377-A | Triazolopyridine compounds as PIM kinase inhibitors | ARRAY BIOPHARMA INC | 2014-01-01 | — | — | CN | disclosed |
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| CN-1169986-A | 2.9-diamino-and 2-amino-8-carbamoyl-4-hydroxy-aldanoic acid amide derivatives | CIBA GEIGY AG (CH) | 1998-01-14 | — | — | CN | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |