Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27504825 | 0.88 | KMT2A (0.44) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL3158102 | 0.82 | NPC1 (0.40) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL3142475 | 0.81 | S1PR4 (0.63) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL27867259 | 0.79 | KMT2A (0.56) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL27744819 | 0.79 | NPC1 (0.40) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL4713894 | 0.79 | S1PR4 (0.40) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL8568292 | 0.79 | ALDH1A1 (0.39) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL27873051 | 0.79 | KMT2A (0.41) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL3167072 | 0.79 | KMT2A (0.41) | KMT2AS1PR4ALDH1A1MEN1HTT | |
| SCHEMBL29903448 | 0.79 | KMT2A (0.41) | KMT2AS1PR4ALDH1A1MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |