SCHEMBL29903448

SCHEMBL29903448

O=[N+]([O-])c1ncccc1CCO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPT P10636 4/20 0.40
ALDH1A1 P00352 4/20 0.40
POLB P06746 2/20 0.40
HTT P42858 1/20 0.40
ESR2 Q92731 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
S1PR4 O95977 1/20 0.40
CYP1A2 P05177 1/20 0.40
RECQL P46063 1/20 0.39
MCL1 Q07820 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CASP1 P29466 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3167072 1.00 KMT2A (0.41) KMT2AMEN1TSHRKDM4EMAPT
SCHEMBL28859293 0.92 ALDH1A1 (0.50) KMT2AMEN1TSHRKDM4EMAPT
SCHEMBL5117671 0.86 ALDH1A1 (0.44) KMT2AMEN1TSHRKDM4EMAPT
SCHEMBL27873051 0.83 KMT2A (0.41) KMT2AMEN1TSHRKDM4EMAPT
SCHEMBL27744819 0.80 NPC1 (0.40) KMT2AMEN1TSHRKDM4EMAPT
SCHEMBL1735333 0.80 MAPT (0.50) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL8560840 0.79 KMT2A (0.46) KMT2AMEN1KDM4EMAPTALDH1A1
SCHEMBL8603295 0.79 NPC1 (0.39) KMT2AMEN1TSHRMAPTALDH1A1
SCHEMBL540885 0.79 ALDH1A1 (0.52) KMT2AMEN1TSHRKDM4EMAPT
SCHEMBL8529530 0.79 KMT2A (0.43) KMT2AMEN1TSHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043770-B Light-induced synthesis method of indole/azaindole compounds 南京大学 2023-09-08 CN disclosed
CN-115043770-A Photoinduction synthesis method of indole/azaindole compound 南京大学 2022-09-13 CN disclosed