Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754062 | 0.80 | CMA1 (0.47) | CCKBRCASP3CMA1GSK3BADK | |
| SCHEMBL8563195 | 0.79 | CCKBR (0.84) | CCKBR | |
| SCHEMBL8405020 | 0.77 | CCKAR (0.56) | CCKBR | |
| SCHEMBL8866387 | 0.76 | CCKBR (0.48) | CCKBRALDH1A1 | |
| SCHEMBL4429210 | 0.76 | GSK3B (0.52) | CASP3CMA1GSK3BADKL3MBTL1 | |
| SCHEMBL3173671 | 0.76 | GSK3B (0.52) | CASP3CMA1GSK3BADKL3MBTL1 | |
| SCHEMBL4422395 | 0.76 | GSK3B (0.52) | CASP3CMA1GSK3BADKL3MBTL1 | |
| SCHEMBL8559078 | 0.76 | BACE1 (0.50) | CCKBRCMA1GSK3BADKL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3854466 | 0.75 | GSK3B (0.51) | CASP3CMA1GSK3BADKL3MBTL1 | |
| SCHEMBL8547144 | 0.74 | CCKBR (0.60) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |