Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560985 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8560984 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562033 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562039 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562035 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL4800164 | 0.81 | HPGD (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL17432673 | 0.81 | HPGD (0.56) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562535 | 0.81 | EPHX2 (0.53) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL8562539 | 0.81 | EPHX2 (0.53) | MTNR1AMTNR1BEPHX2GAAMAPT | |
| SCHEMBL2031526 | 0.81 | EPHX2 (0.53) | MTNR1AMTNR1BEPHX2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |