SCHEMBL8561106

SCHEMBL8561106

CCCCCCn1c(O)cc(C)c(C#N)c1=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.57
USP2 O75604 1/20 0.57
LMNA P02545 3/20 0.53
KMT2A Q03164 8/20 0.51
MEN1 O00255 7/20 0.51
MAPT P10636 5/20 0.51
HPGD P15428 1/20 0.44
THRB P10828 1/20 0.43
HSD17B10 Q99714 3/20 0.42
ALDH1A1 P00352 4/20 0.42
MAPK1 P28482 1/20 0.42
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GAA P10253 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
UPP1 Q16831 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208611 1.00 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10889819 1.00 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10887425 1.00 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL8125127 1.00 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL11129423 0.98 KDM4E (0.59) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL623429 0.94 KDM4E (0.60) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10768477 0.94 KDM4E (0.56) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10766144 0.92 KDM4E (0.57) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10346288 0.92 KDM4E (0.50) KDM4EUSP2LMNAKMT2AMEN1
SCHEMBL10622779 0.92 KDM4E (0.50) KDM4EUSP2LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299289-B Pyridone azo disperse dye containing sulfonate group and synthesis method thereof 江苏迪安化工有限公司 2020-11-24 CN disclosed
CN-108299289-A A kind of pyridinone azo dispersion dyes and its synthetic method containing sulfonate group 浙江山峪科技股份有限公司 2018-07-20 CN disclosed
US-20090053455-A1 OPTICAL RECORDING MEDIUM, METAL COMPLEX COMPOUND AND ORGANIC DYE COMPOUND MITSUBISHI KAGAKU MEDIA CO., LTD (JP) 2009-02-26 US disclosed
EP-1864822-A1 OPTICAL RECORDING MEDIUM, METAL COMPLEX COMPOUND AND ORGANIC DYE COMPOUND Mitsubishi Kagaku Media Corporation, Ltd. (JP) 2007-12-12 EP disclosed
US-5719288-A FOR TEXTILES BASF AKTIENGESELLSCHAFT (DE) 1998-02-17 US disclosed
EP-0736069-B1 PYRIDONE DYES BASF AG (DE) 1997-09-24 EP disclosed
EP-0736069-A1 PYRIDONE DYES BASF AG (DE) 1996-10-09 EP disclosed
WO-1995017470-A1 PYRIDONE DYES BASF AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
EP-0442466-B1 Thermal transfer recording sheet and ink composition for producing the same MITSUBISHI CHEM IND (JP) 1995-01-18 EP disclosed
US-5246911-A Binder and pyridone type azo dye MITSUBISHI KASEI CORPORATION (JP) 1993-09-21 US disclosed
EP-0085823-B1 DYE MIXTURE, PROCESS FOR ITS PREPARATION AND ITS USE IN DYEING AND PRINTING HYDROPHOBIC TEXTILE MATERIAL CIBA-GEIGY AG (CH) 1986-02-05 EP disclosed
EP-0040582-B1 AZO COMPOUNDS CIBA-GEIGY AG (CH) 1985-03-20 EP disclosed
EP-0041042-B1 AZO COMPOUNDS CIBA-GEIGY AG (CH) 1984-12-05 EP disclosed
EP-0109527-A1 Water-insoluble monoazo dyestuffs, methods for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1984-05-30 EP disclosed
EP-0038439-B1 DYESTUFF MIXTURES, METHOD FOR THEIR PREPARATION, THE COMPONENT DYESTUFFS AND THEIR USE IN DYEING AND PRINTING SYNTHETIC, HYDROPHOBIC FIBRE MATERIAL CASSELLA Aktiengesellschaft (DE) 1983-05-04 EP disclosed
EP-0041042-A1 Azo compounds CIBA-GEIGY AG (CH) 1981-12-02 EP disclosed
EP-0040582-A2 Azo compounds CIBA-GEIGY AG (CH) 1981-11-25 EP disclosed
EP-0038439-A1 Dyestuff mixtures, method for their preparation, the component dyestuffs and their use in dyeing and printing synthetic, hydrophobic fibre material CASSELLA Aktiengesellschaft (DE) 1981-10-28 EP disclosed
US-4233399-A Photographic elements containing amino-substituted hydroxy-pyridones CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-11-11 US disclosed
US-4182886-A OPTICAL FILTERS IN COLOR PHOTOGRAPHY CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090053455-A1 OPTICAL RECORDING MEDIUM, METAL COMPLEX COMPOUND AND ORGANIC DYE COMPOUND KCNJ2, KCNN2, KCNN3 KDM4E 1932/4885USP2 4802/4885LMNA 1934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.