Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567383 | 0.80 | EGFR (0.36) | KDM4AKDM4BMAPTEGFRALDH1A1 | |
| SCHEMBL8567381 | 0.80 | EGFR (0.36) | KDM4AKDM4BMAPTEGFRALDH1A1 | |
| SCHEMBL17801662 | 0.77 | ALDH1A1 (0.45) | MAPTEGFRALDH1A1MEN1KMT2A | |
| SCHEMBL31161596 | 0.75 | ALDH1A1 (0.35) | MAPTEGFRALDH1A1MEN1KMT2A | |
| SCHEMBL29594574 | 0.74 | MAPT (0.66) | NFE2L2CYP19A1MAPTFBP1ALDH1A1 | |
| SCHEMBL5442818 | 0.74 | MAPT (0.66) | NFE2L2CYP19A1MAPTFBP1ALDH1A1 | |
| SCHEMBL1578978 | 0.74 | MAPT (0.66) | NFE2L2CYP19A1MAPTFBP1ALDH1A1 | |
| SCHEMBL1578983 | 0.74 | MAPT (0.66) | NFE2L2CYP19A1MAPTFBP1ALDH1A1 | |
| SCHEMBL8562885 | 0.74 | NFE2L2 (0.45) | NFE2L2CYP19A1TAAR1MAPTFBP1 | |
| SCHEMBL8566996 | 0.74 | CYP11B1 (0.50) | NFE2L2CYP19A1TAAR1MAPTFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |