Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242140 | 0.93 | MAPT (0.50) | PPARGPPARAMAPT | |
| SCHEMBL22748859 | 0.87 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL12844280 | 0.86 | MAPT (0.53) | MAPT | |
| SCHEMBL28509682 | 0.85 | S1PR2 (0.55) | MAPT | |
| SCHEMBL10771261 | 0.84 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL10774024 | 0.84 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL10773021 | 0.84 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL3872175 | 0.82 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL14122353 | 0.81 | PPARG (0.57) | PPARGPPARAMAPT | |
| SCHEMBL4737345 | 0.80 | GPR3 (0.54) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |