Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561443 | 0.87 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL10774024 | 0.84 | PPARG (0.65) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL10773021 | 0.84 | PPARG (0.65) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL10771261 | 0.84 | PPARG (0.65) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL17295274 | 0.83 | ATM (0.44) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL3872175 | 0.82 | PPARG (0.62) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL17295146 | 0.81 | TNKS2 (0.60) | PPARGPPARA | |
| SCHEMBL11222303 | 0.81 | ATM (0.43) | PPARGPPARACYP1A2CYP3A4 | |
| SCHEMBL4737345 | 0.80 | GPR3 (0.54) | PPARACYP3A4 | |
| SCHEMBL9485313 | 0.80 | HTR1A (0.72) | PPARGPPARACYP1A2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245297-A1 | PYRROLE DERIVATIVES AS ACC INHIBITORS | ALMIRALL, S.A. (ES) | 2020-12-10 | — | — | WO | disclosed |