Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.37 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.37 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.37 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562365 | 0.75 | ACHE (0.40) | CYP2C9HTR2CCYP1A2TSHRHTR2A | |
| SCHEMBL8597133 | 0.74 | HTR2A (0.39) | CYP3A4HTR2CCYP1A2HTR2AKCNH2 | |
| SCHEMBL8567840 | 0.74 | POLB (0.47) | POLBTSHRMAPTMEN1KMT2A | |
| SCHEMBL13607109 | 0.72 | PTGES (0.38) | POLBTSHRMAPTMEN1KMT2A | |
| SCHEMBL8561101 | 0.70 | POLB (0.53) | POLBCYP3A4CYP1A2TSHRMAPT | |
| SCHEMBL4465119 | 0.70 | HRH1 (0.41) | CYP3A4CYP2C9PRKCQMAPTMAPK1 | |
| SCHEMBL202663 | 0.69 | POLB (0.51) | POLBCYP1A2TSHRMAPTMEN1 | |
| SCHEMBL1033969 | 0.69 | POLB (0.51) | POLBHTR2CKCNH2MAPTMEN1 | |
| SCHEMBL4727431 | 0.69 | POLB (0.51) | POLBCYP1A2TSHRMAPTMEN1 | |
| SCHEMBL15824026 | 0.69 | POLB (0.51) | POLBCYP3A4CYP1A2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |