Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 7/20 | 0.34 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569473 | 0.85 | BCHE (0.40) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8563673 | 0.79 | CYP3A4 (0.36) | KDM1AKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL8211008 | 0.68 | KMT2A (0.46) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8563654 | 0.68 | KDM1A (0.37) | KDM1AMAOAMAOBKDM1BKCNH2 | |
| SCHEMBL8564523 | 0.67 | KDM4E (0.53) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8561732 | 0.66 | PRKAA2 (0.43) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL28528656 | 0.66 | CYP3A4 (0.48) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL11667039 | 0.65 | MAPT (0.48) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8561932 | 0.65 | KDM4E (0.46) | KMT2AMEN1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8562365 | 0.65 | ACHE (0.40) | KMT2AMEN1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |