Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561932 | 0.84 | KDM4E (0.46) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL20291524 | 0.84 | CYP3A4 (0.61) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8211008 | 0.81 | KMT2A (0.46) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL28579892 | 0.80 | S100A4 (0.50) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8567950 | 0.80 | CYP3A4 (0.47) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11667039 | 0.78 | MAPT (0.48) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL21632212 | 0.76 | MAOA (0.53) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8564523 | 0.76 | KDM4E (0.53) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL21632211 | 0.75 | CYP3A4 (0.50) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL8564301 | 0.75 | KDM4E (0.47) | CYP3A4KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113150144-A | Tumor necrosis factor-like ligand 1A specific antibody, and composition and application thereof | 辉瑞大药厂 | 2021-07-23 | — | — | CN | disclosed |
| CN-105814081-B | Tumor necrosis factor-like ligand 1A specific antibody, and composition and application thereof | 辉瑞大药厂 | 2021-02-02 | — | — | CN | disclosed |