Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568547 | 0.89 | KDM4E (0.47) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8560879 | 0.83 | KDM4E (0.51) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21750427 | 0.82 | HRH2 (0.46) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8814790 | 0.82 | CXCR4 (0.43) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8562390 | 0.81 | CYP2D6 (0.54) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1301323 | 0.80 | HRH3 (0.49) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24562861 | 0.79 | MEN1 (0.50) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL561818 | 0.79 | HRH2 (0.44) | LMNAALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1950623 | 0.79 | HRH3 (0.48) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8560963 | 0.79 | KDM4E (0.52) | LMNAALDH1A1SMN1; SMN2KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705497-A | INOTROPIC, ANTIARRHYTHMIA AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-01-06 | — | — | US | disclosed |