Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561623 | 0.89 | LMNA (0.46) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9423512 | 0.84 | MEN1 (0.46) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9423515 | 0.82 | MEN1 (0.45) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL8564311 | 0.82 | KMT2A (0.49) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5953471 | 0.81 | SLC18A3 (0.49) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL26698256 | 0.81 | MEN1 (0.44) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL6971664 | 0.81 | SLC18A3 (0.49) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10386591 | 0.80 | KMT2A (0.51) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7421281 | 0.79 | SLC18A3 (0.48) | KDM4EALDH1A1MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6498838 | 0.79 | SLC18A3 (0.48) | KDM4EALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705497-A | INOTROPIC, ANTIARRHYTHMIA AGENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-01-06 | — | — | US | disclosed |