Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.33 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559500 | 0.89 | RARA (0.33) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8563491 | 0.88 | RARA (0.31) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294002 | 0.77 | PDE4B (0.41) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8892652 | 0.76 | RARA (0.33) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6292573 | 0.74 | RARB (0.50) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294125 | 0.73 | HPGD (0.47) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6297168 | 0.71 | RARA (0.40) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6292700 | 0.71 | RARA (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7859347 | 0.70 | RARA (0.38) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294021 | 0.70 | RARA (0.69) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808124-A | BINDING TO RETINOID RECEPTORS | ALLERGAN (US) | 1998-09-15 | — | — | US | disclosed |
| US-5723666-A | USEFUL AS REGULATORS OF CELL PROLIFERATION AND DIFFERENTIATION | ALLERGAN (US) | 1998-03-03 | — | — | US | disclosed |