Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.33 |
| ▸ | RARB | P10826 | 4/20 | 0.33 |
| ▸ | RARG | P13631 | 4/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CDC25A | P30304 | 2/20 | 0.31 |
| ▸ | CDC25B | P30305 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294002 | 0.82 | PDE4B (0.41) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6292573 | 0.79 | RARB (0.50) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294125 | 0.78 | HPGD (0.47) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8893716 | 0.77 | S100A4 (0.39) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8561650 | 0.76 | RARA (0.33) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6292700 | 0.75 | RARA (0.44) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6297168 | 0.73 | RARA (0.40) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL7859347 | 0.73 | RARA (0.38) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294021 | 0.73 | RARA (0.69) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8772575 | 0.73 | RARA (0.68) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048672-A2 | SUBSTITUTED TETRAHYDRONAPHTHALENE AND DIHYDRONAPHTHALENE DERIVATIVES HAVING RETINOID AND/OR RETINOID ANTAGONIST-LIKE BIOLOGICAL ACTIVITY | ALLERGAN SALES, INC. (US) | 1997-12-24 | — | — | WO | disclosed |