Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.44 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.44 |
| ▸ | SMPD3 | Q9NY59 | 5/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569098 | 0.91 | KCNH2 (0.42) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| SCHEMBL8569090 | 0.91 | KCNH2 (0.42) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| SCHEMBL8564024 | 0.90 | SCN5A (0.42) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| SCHEMBL14497283 | 0.90 | SCN5A (0.43) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| Hydrochloric Acid SCHEMBL7502027 | 0.90 | KCNH2 (0.42) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| Hydrochloric Acid SCHEMBL7502024 | 0.90 | KCNH2 (0.42) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| Hydrochloric Acid SCHEMBL8576586 | 0.89 | SCN5A (0.41) | DYRK3PIM3SRPK1CSNK1G1SCN5A | |
| SCHEMBL27366399 | 0.89 | KCNH2 (0.44) | DYRK3PIM3SRPK1CSNK1G1SMPD3 | |
| Hydrochloric Acid SCHEMBL7504569 | 0.88 | KCNH2 (0.43) | DYRK3PIM3SRPK1CSNK1G1SMPD3 | |
| SCHEMBL7501829 | 0.88 | SCN5A (0.38) | DYRK3PIM3SRPK1CSNK1G1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | claimed |
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5726182-A | TREATMENT OF BACTERIAL INFECTIONS | ABBOTT LABORATORIES (US) | 1998-03-10 | — | — | US | disclosed |
| US-5599816-A | BACTERICIDE | ABBOTT LABORATORIES (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |