Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 5/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 1/20 | 0.33 |
| ▸ | TXK | P42681 | 1/20 | 0.33 |
| ▸ | BMX | P51813 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7504569 | 0.99 | KCNH2 (0.43) | KCNH2SCN5ASLC2A1BTKDYRK3 | |
| SCHEMBL8562871 | 0.95 | KCNH2 (0.41) | KCNH2SCN5ASLC2A1BTKEGFR | |
| SCHEMBL27350832 | 0.94 | KCNH2 (0.41) | KCNH2SCN5ASLC2A1BTKDYRK3 | |
| Hydrochloric Acid SCHEMBL8562517 | 0.94 | KCNH2 (0.41) | KCNH2SCN5ASLC2A1BTKEGFR | |
| Hydrochloric Acid SCHEMBL7507501 | 0.94 | KCNH2 (0.41) | KCNH2SCN5ASLC2A1BTKDYRK3 | |
| SCHEMBL8566628 | 0.90 | SLC2A1 (0.47) | KCNH2SCN5ASLC2A1BTKDYRK3 | |
| SCHEMBL8561869 | 0.89 | DYRK3 (0.44) | KCNH2SCN5ABTKDYRK3PIM3 | |
| SCHEMBL14497283 | 0.88 | SCN5A (0.43) | KCNH2SCN5ABTKDYRK3PIM3 | |
| SCHEMBL27451746 | 0.88 | KCNH2 (0.41) | KCNH2SCN5ASLC2A1BTKDYRK3 | |
| Hydrochloric Acid SCHEMBL27367343 | 0.87 | KCNH2 (0.41) | KCNH2SCN5ASLC2A1BTKDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053188-C | Quinolizinone type compounds | ABBOTT LAB (US) | 2000-06-07 | — | — | CN | disclosed |
| CN-1137273-A | Quinolizinone type compounds | ABBOTT LAB (US) | 1996-12-04 | — | — | CN | disclosed |