Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.62 |
| ▸ | RARG | P13631 | 14/20 | 0.62 |
| ▸ | RARA | P10276 | 7/20 | 0.62 |
| ▸ | RARB | P10826 | 7/20 | 0.62 |
| ▸ | RXRB | P28702 | 2/20 | 0.62 |
| ▸ | RXRG | P48443 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 10/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561873 | 1.00 | RXRA (0.62) | RXRARARGRARARARBRXRB | |
| SCHEMBL8146559 | 0.90 | RXRA (0.65) | RXRARARGRARARARBRXRB | |
| SCHEMBL8151971 | 0.90 | RXRA (0.65) | RXRARARGRARARARBRXRB | |
| SCHEMBL8151970 | 0.90 | RXRA (0.65) | RXRARARGRARARARBRXRB | |
| SCHEMBL8560235 | 0.84 | RXRA (0.58) | RXRARARGRARARARBRXRB | |
| SCHEMBL8560229 | 0.84 | RXRA (0.58) | RXRARARGRARARARBRXRB | |
| SCHEMBL7689448 | 0.83 | RARG (0.46) | RXRARARGRARARARBRXRB | |
| SCHEMBL7689450 | 0.83 | RARG (0.46) | RXRARARGRARARARBRXRB | |
| SCHEMBL7689451 | 0.83 | RARG (0.46) | RXRARARGRARARARBRXRB | |
| SCHEMBL8850686 | 0.80 | RXRA (0.74) | RXRARARGRARARARBRXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0679628-B1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CIRD GALDERMA (FR) | 1998-04-22 | — | — | EP | claimed |
| EP-0679628-A1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1995-11-02 | — | — | EP | claimed |
| EP-0679628-B1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CIRD GALDERMA (FR) | 1998-04-22 | — | — | EP | disclosed |
| EP-0679628-A1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1995-11-02 | — | — | EP | disclosed |