Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 12/20 | 0.46 |
| ▸ | RARA | P10276 | 6/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | RXRA | P19793 | 14/20 | 0.44 |
| ▸ | PPARG | P37231 | 9/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | ESRRA | P11474 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689450 | 1.00 | RARG (0.46) | RARGRARARARBRXRAPPARG | |
| SCHEMBL7689448 | 1.00 | RARG (0.46) | RARGRARARARBRXRAPPARG | |
| SCHEMBL7686291 | 0.87 | RARG (0.49) | RARGRARARARBRXRAPPARG | |
| SCHEMBL7686292 | 0.87 | RARG (0.49) | RARGRARARARBRXRAPPARG | |
| SCHEMBL7686290 | 0.87 | RARG (0.49) | RARGRARARARBRXRAPPARG | |
| SCHEMBL8561875 | 0.83 | RXRA (0.62) | RARGRARARARBRXRAPPARG | |
| SCHEMBL8561873 | 0.83 | RXRA (0.62) | RARGRARARARBRXRAPPARG | |
| SCHEMBL7685329 | 0.80 | RXRA (0.40) | RARGRARARARBRXRAPPARG | |
| SCHEMBL8146546 | 0.80 | RXRA (0.68) | RARGRARARARBRXRAPPARG | |
| SCHEMBL8145943 | 0.80 | RXRA (0.68) | RARGRARARARBRXRAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37947-E1 | Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2002-12-31 | — | — | US | claimed |
| EP-0679628-B1 | Polyene derivatives, pharmaceutical and cosmetic composition containing them and their use | CIRD GALDERMA (FR) | 1998-04-22 | — | — | EP | claimed |
| US-5705167-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-06 | — | — | US | claimed |
| US-RE37947-E1 | Aromatic polyenic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2002-12-31 | — | — | US | disclosed |
| US-5705167-A | TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR, BONE AND OPHTHALMOLOGICAL DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-01-06 | — | — | US | disclosed |