Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 3/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292880 | 0.73 | RARA (0.49) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6292881 | 0.73 | RARA (0.49) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8165227 | 0.70 | HTR2A (0.36) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8644020 | 0.67 | RARA (0.37) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8644015 | 0.67 | PPARG (0.45) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8772736 | 0.67 | RARB (0.38) | MCL1RARARARBRARGRXRA | |
| SCHEMBL31470216 | 0.66 | MCL1 (0.48) | MCL1MYCALDH1A1LMNA | |
| SCHEMBL8772731 | 0.64 | RARA (0.50) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8561897 | 0.63 | RARA (0.40) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL9295862 | 0.62 | RARA (0.46) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808124-A | BINDING TO RETINOID RECEPTORS | ALLERGAN (US) | 1998-09-15 | — | — | US | disclosed |