Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 18/20 | 0.40 |
| ▸ | RARB | P10826 | 18/20 | 0.40 |
| ▸ | RARG | P13631 | 17/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.40 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363055 | 0.75 | RARA (0.60) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8562260 | 0.74 | NPC1 (0.30) | — | |
| SCHEMBL6420934 | 0.74 | RARA (0.49) | RARARARBRARG | |
| SCHEMBL8903103 | 0.74 | RARA (0.52) | RARARARBRARG | |
| SCHEMBL8902592 | 0.73 | RARA (0.67) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294083 | 0.71 | RARA (0.68) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8772736 | 0.71 | RARB (0.38) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8634040 | 0.69 | RARA (0.32) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL6294123 | 0.69 | GAA (0.31) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8634037 | 0.69 | RARA (0.32) | RARARARBRARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808124-A | BINDING TO RETINOID RECEPTORS | ALLERGAN (US) | 1998-09-15 | — | — | US | disclosed |