Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.49 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418876 | 0.74 | KDM4E (0.42) | KDM4EL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL7562618 | 0.69 | KDM4E (0.46) | KDM4EL3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL11666619 | 0.68 | KDM4E (0.61) | KDM4EL3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL11272953 | 0.68 | KDM4E (0.37) | KDM4EL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL29142977 | 0.67 | KDM4E (0.48) | KDM4EL3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL13774950 | 0.66 | CYP3A4 (0.54) | KDM4EL3MBTL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL5049130 | 0.66 | CYP3A4 (0.59) | KDM4EL3MBTL1ALDH1A1CYP3A4MAPT | |
| SCHEMBL11270436 | 0.66 | KDM4E (0.38) | KDM4EL3MBTL1ALDH1A1GAAGLA | |
| SCHEMBL10059379 | 0.63 | ATM (0.43) | KDM4EL3MBTL1ALDH1A1HPGDGAA | |
| SCHEMBL11248370 | 0.63 | L3MBTL1 (0.67) | KDM4EL3MBTL1ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942905-A1 | 3-AMINO-1-CYANOPHENYL-URACILS | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998025909-A1 | 3-AMINO-1-CYANOPHENYL-URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |