Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15688189 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL8561900 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL11272953 | 0.74 | KDM4E (0.37) | KDM4EGRIA1GRIA3PDE4DALDH1A1 | |
| SCHEMBL11270436 | 0.72 | KDM4E (0.38) | KDM4EGRIA1GRIA3PDE4DALDH1A1 | |
| SCHEMBL10059379 | 0.69 | ATM (0.43) | KDM4EGRIA1GRIA3PDE4DALDH1A1 | |
| SCHEMBL11248370 | 0.69 | L3MBTL1 (0.67) | KDM4EGRIA1GRIA3PDE4DALDH1A1 | |
| SCHEMBL1884359 | 0.66 | GRIA1 (0.61) | KDM4EGRIA1GRIA3PDE4DALDH1A1 | |
| SCHEMBL25156033 | 0.66 | IMPDH2 (0.58) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL30344860 | 0.66 | IMPDH2 (0.58) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL3962760 | 0.65 | SMN1; SMN2 (0.53) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0942905-A1 | 3-AMINO-1-CYANOPHENYL-URACILS | BAYER AG (DE) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998025909-A1 | 3-AMINO-1-CYANOPHENYL-URACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-18 | — | — | WO | disclosed |