Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666658 | 0.89 | MAPT (0.66) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL143083 | 0.89 | MAPT (0.66) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL2996981 | 0.86 | ALDH1A1 (0.72) | NPC1RAB9ATDP1USP2ALDH1A1 | |
| SCHEMBL2996977 | 0.86 | ALDH1A1 (0.72) | NPC1RAB9ATDP1USP2ALDH1A1 | |
| SCHEMBL8559227 | 0.84 | ALDH1A1 (0.78) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL2998871 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9ATDP1USP2ALDH1A1 | |
| SCHEMBL2998874 | 0.80 | ALDH1A1 (0.58) | NPC1RAB9ATDP1USP2ALDH1A1 | |
| SCHEMBL4029206 | 0.79 | HDAC2 (0.76) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL29060766 | 0.79 | HDAC2 (0.76) | NPC1RAB9AMAPTTDP1ALDH1A1 | |
| SCHEMBL10033954 | 0.78 | CYP1B1 (0.75) | NPC1RAB9AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| CN-1089947-A | New heterogeneous ring compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-27 | — | — | CN | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |