Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562050 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HPGDPTGS2PRMT1ESR1 | |
| SCHEMBL6965728 | 0.95 | ALDH1A1 (0.62) | ALDH1A1HPGDPTGS2PRMT1ESR1 | |
| SCHEMBL6965731 | 0.95 | ALDH1A1 (0.62) | ALDH1A1HPGDPTGS2PRMT1ESR1 | |
| SCHEMBL25191350 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25195117 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8565875 | 0.80 | CA12 (0.53) | ALDH1A1HPGDPTGS2ESR1CA12 | |
| SCHEMBL8565879 | 0.80 | CA12 (0.53) | ALDH1A1HPGDPTGS2ESR1CA12 | |
| SCHEMBL10414593 | 0.79 | PRMT1 (0.71) | ALDH1A1HPGDPRMT1CYP1A2CYP3A4 | |
| SCHEMBL10414595 | 0.79 | PRMT1 (0.71) | ALDH1A1HPGDPRMT1CYP1A2CYP3A4 | |
| SCHEMBL7452771 | 0.78 | PTGS2 (0.77) | ALDH1A1PTGS2ESR1HCAR2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5750699-A | HALOGENATING OF CORRESPONDING COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5574042-A | ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 1996-11-12 | — | — | US | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |