Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12912123 | 0.84 | BCHE (0.51) | BCHEGNAI3GNAO1GNAI1 | |
| SCHEMBL24661418 | 0.84 | CYP3A4 (0.41) | NPC1L3MBTL1 | |
| SCHEMBL24661420 | 0.84 | CYP3A4 (0.41) | NPC1L3MBTL1 | |
| SCHEMBL9277201 | 0.81 | GNAO1 (0.46) | BCHEGNAI3GNAO1GNAI1 | |
| SCHEMBL771415 | 0.80 | NPC1 (0.37) | NPC1L3MBTL1 | |
| SCHEMBL12464724 | 0.80 | NPC1 (0.41) | NPC1L3MBTL1 | |
| SCHEMBL12911893 | 0.79 | BCHE (0.45) | BCHE | |
| SCHEMBL14369074 | 0.77 | SMN1; SMN2 (0.45) | NPC1L3MBTL1 | |
| SCHEMBL22436112 | 0.77 | SMN1; SMN2 (0.45) | NPC1L3MBTL1 | |
| SCHEMBL14394397 | 0.76 | CHRM5 (0.46) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853615-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997010212-A1 | PIPERIDINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 1997-03-20 | — | — | WO | disclosed |