Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 6/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 6/20 | 0.40 |
| ▸ | DRD1 | P21728 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 6/20 | 0.40 |
| ▸ | DRD5 | P21918 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25654272 | 0.88 | HRH3 (0.40) | GNAO1GNAI3GNAI1DRD1DRD4 | |
| SCHEMBL25654271 | 0.88 | HRH3 (0.40) | GNAO1GNAI3GNAI1DRD1DRD4 | |
| SCHEMBL24672773 | 0.88 | GNAO1 (0.56) | GNAO1GNAI3GNAI1 | |
| SCHEMBL27364662 | 0.86 | GNAO1 (0.50) | GNAO1GNAI3GNAI1BCHEHTR1A | |
| SCHEMBL22856570 | 0.86 | CHRM2 (0.41) | GNAO1GNAI3GNAI1 | |
| SCHEMBL7739926 | 0.85 | GUSB (0.48) | GNAO1GNAI3GNAI1EBPSIGMAR1 | |
| SCHEMBL25469357 | 0.83 | GNAO1 (0.44) | GNAO1GNAI3GNAI1BCHE | |
| SCHEMBL23986827 | 0.82 | GNAI3 (0.40) | GNAO1GNAI3GNAI1 | |
| SCHEMBL17033973 | 0.82 | LIPC (0.38) | GNAO1GNAI3GNAI1 | |
| SCHEMBL26280657 | 0.82 | LIPC (0.38) | GNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995003421-A1 | PROCESS FOR THE ENZYMATIC PREPARATION OF OPTICALLY ACTIVE N-SUBSTITUTED-3-PYRROLIDINOL | DSM N.V. (NL) | 1995-02-02 | — | — | WO | disclosed |