Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662479 | 0.92 | MAPKAPK2 (0.58) | MAPKAPK2S1PR1 | |
| SCHEMBL7666158 | 0.89 | MAPKAPK2 (0.59) | MAPKAPK2ADRA1AHTR1DHTR1BEGFR | |
| SCHEMBL11682262 | 0.83 | MAPKAPK2 (0.59) | MAPKAPK2S1PR1ADRA1AEGFRIGF1R | |
| SCHEMBL8757765 | 0.82 | MAPKAPK2 (0.60) | MAPKAPK2ADRA1A | |
| SCHEMBL28495179 | 0.82 | GABRA1 (0.52) | MAPKAPK2HTR1DHTR1BEGFRIGF1R | |
| SCHEMBL8562199 | 0.81 | MAPKAPK2 (0.50) | MAPKAPK2ADRA1AHTR1DHTR1BEGFR | |
| SCHEMBL11842906 | 0.80 | MAPKAPK2 (0.54) | MAPKAPK2ADRA1AHTR1DHTR1BEGFR | |
| SCHEMBL8756935 | 0.77 | GABRA1 (0.54) | MAPKAPK2ADRA1AEGFR | |
| SCHEMBL7655639 | 0.76 | HTR1D (0.50) | MAPKAPK2ADRA1AHTR1DHTR1BEGFR | |
| SCHEMBL11831865 | 0.75 | HTR1D (0.66) | MAPKAPK2HTR1DHTR1BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998006402-A1 | TREATMENT OF THE COMMON COLD OR ALLERGIC RHINITIS | ELI LILLY AND COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
| US-5708187-A | MIGRANE HEADACHES | ELI LILLY AND COMPANY (US) | 1998-01-13 | — | — | US | disclosed |