Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.44 |
| ▸ | PTPRF | P10586 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.43 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562218 | 1.00 | LMNA (0.55) | LMNAPTGER4PTPN1PTPRFPTPRA | |
| SCHEMBL8557948 | 1.00 | LMNA (0.55) | LMNAPTGER4PTPN1PTPRFPTPRA | |
| SCHEMBL13418750 | 0.80 | PTPN1 (0.63) | LMNAPTGER4PTPN1PTPRFPTPRA | |
| SCHEMBL8559217 | 0.78 | PPARG (0.53) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8559220 | 0.78 | PPARG (0.53) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8564894 | 0.77 | PPARG (0.64) | PTPN1PTPN7MAPTSLC1A3SLC1A2 | |
| SCHEMBL8560729 | 0.77 | PPARG (0.64) | PTPN1PTPN7MAPTSLC1A3SLC1A2 | |
| SCHEMBL8559718 | 0.77 | PPARG (0.64) | PTPN1PTPN7MAPTSLC1A3SLC1A2 | |
| SCHEMBL9235405 | 0.77 | LMNA (0.57) | LMNAPTGER4MAPTALDH1A1ACSL1 | |
| SCHEMBL9235410 | 0.77 | LMNA (0.57) | LMNAPTGER4MAPTALDH1A1ACSL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | claimed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | claimed |
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |