Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570002 | 0.90 | AR (0.57) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL532856 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL12569892 | 0.88 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL18580876 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL17512389 | 0.85 | GAA (0.64) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL5149916 | 0.84 | PRSS1 (0.56) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL2687080 | 0.84 | LMNA (0.56) | ALDH1A1HPGDNPSR1VCAM1MAPT | |
| SCHEMBL11790540 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL5913915 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDNPSR1PRSS1VCAM1 | |
| SCHEMBL5155524 | 0.82 | AR (0.55) | ALDH1A1HPGDNPSR1PRSS1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0702004-A2 | 2,9-diamino- and 2-amino-8-carbamoyl-4-hydroxy-alkanoic acid amid derivatives | CIBA-GEIGY AG (CH) | 1996-03-20 | — | — | EP | disclosed |