SCHEMBL8562465

CC(=O)Nc1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	BDKRB2	P30411	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8562460	1.00	BDKRB2 (1.00)	BDKRB2
SCHEMBL8565043	0.95	BDKRB2 (0.91)	BDKRB2
SCHEMBL8565041	0.95	BDKRB2 (0.91)	BDKRB2
Hydrochloric Acid SCHEMBL8563027	0.95	BDKRB2 (0.92)	BDKRB2
Hydrochloric Acid SCHEMBL8563030	0.95	BDKRB2 (0.92)	BDKRB2
SCHEMBL8565896	0.94	BDKRB2 (1.00)	BDKRB2
SCHEMBL8565901	0.94	BDKRB2 (1.00)	BDKRB2
Hydrochloric Acid SCHEMBL8563293	0.94	BDKRB2 (1.00)	BDKRB2
Hydrochloric Acid SCHEMBL8563289	0.94	BDKRB2 (1.00)	BDKRB2
SCHEMBL8560900	0.94	BDKRB2 (0.88)	BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0596406-B1	Imidazo (1,2-a) Pyridines as bradykinin antagonists	FUJISAWA PHARMACEUTICAL CO (JP)	1998-12-16	—	—	EP	disclosed
US-5574042-A	ANTAGONIST FOR BRADYKININS AS ANTIALLERGENS, AUTOIMMUNE DISEASES, ANTIINFLAMMATORY AGENTS, SHOCK OR PAIN	FUJISAWA PHARMACEUTICAL CO., LTD (JP)	1996-11-12	—	—	US	disclosed
EP-0596406-A1	Imidazo (1,2-a) Pyridines as bradykinin antagonists	FUJISAWA PHARMACEUTICAL CO., LTD. (JP)	1994-05-11	—	—	EP	disclosed