Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | KYNU | Q16719 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562681 | 1.00 | SLC7A5 (0.38) | SLC7A5SLC1A3SLC1A1HSD17B10SLC1A2 | |
| SCHEMBL10565313 | 0.77 | KDM4E (0.41) | HSD17B10 | |
| SCHEMBL503133 | 0.71 | GRIA1 (0.41) | SLC1A3HSD17B10GRIA1GRIA2GRIA4 | |
| SCHEMBL15208985 | 0.71 | GRIA1 (0.41) | SLC1A3HSD17B10GRIA1GRIA2GRIA4 | |
| SCHEMBL21299181 | 0.71 | GRIA1 (0.41) | SLC1A3HSD17B10GRIA1GRIA2GRIA4 | |
| SCHEMBL8562384 | 0.71 | MAPT (0.43) | SLC7A5SLC1A3SLC1A1SLC1A2DPP7 | |
| SCHEMBL8560718 | 0.71 | SLC1A3 (0.37) | SLC7A5SLC1A3SLC1A1HSD17B10SLC1A2 | |
| SCHEMBL8562387 | 0.71 | MAPT (0.43) | SLC7A5SLC1A3SLC1A1SLC1A2DPP7 | |
| SCHEMBL10568507 | 0.68 | ALDH1A1 (0.39) | — | |
| SCHEMBL8752907 | 0.68 | CYP19A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843997-A | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1998-12-01 | — | — | US | disclosed |
| US-5576323-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-11-19 | — | — | US | disclosed |