Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10566564 | 0.85 | SLC6A3 (0.38) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL10492450 | 0.81 | PTGS2 (0.38) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL8562687 | 0.77 | SLC7A5 (0.38) | HSD17B10 | |
| SCHEMBL10821052 | 0.74 | — | — | |
| SCHEMBL10821215 | 0.71 | ALDH1A1 (0.36) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5440264 | 0.68 | MAPT (0.49) | CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL17627038 | 0.66 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL503134 | 0.64 | TP53 (0.31) | — | |
| SCHEMBL1155636 | 0.64 | PPARG (0.40) | KDM4EALDH1A1HPGDMAPK1SMN1; SMN2 | |
| Propionic Acid SCHEMBL18668396 | 0.64 | FFAR3 (0.42) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076454-A1 | COMBINATION TREATMENT OF LIVER DISEASES USING INTEGRIN INHIBITORS | Novartis AG (CH) | 2022-10-26 | — | — | EP | disclosed |
| US-4829074-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-09 | — | — | US | disclosed |
| EP-0194064-A2 | Azolyl substituted aralkyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | disclosed |