Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GNRHR | P30968 | 3/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21947205 | 0.77 | MEN1 (0.58) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL3968508 | 0.77 | MEN1 (0.58) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL8597971 | 0.73 | KDM4E (1.00) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL2369095 | 0.69 | PARP1 (1.00) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL8598047 | 0.69 | GAA (0.63) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL8599112 | 0.68 | KDM4E (0.65) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL8562794 | 0.68 | KDM4E (0.56) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL11556832 | 0.67 | ALOX15 (0.50) | MEN1KMT2AMAPTPOLBL3MBTL1 | |
| SCHEMBL3968217 | 0.66 | KDM4E (0.44) | KDM4EHPGDPARP1MEN1KMT2A | |
| SCHEMBL9674513 | 0.66 | DRD4 (0.60) | KDM4EHPGDPARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |