Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21684541 | 0.72 | ALDH1A1 (0.41) | ALDH1A1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL3537609 | 0.71 | PTGER4 (0.56) | KDM4EHSD17B10 | |
| SCHEMBL2927140 | 0.71 | PPARG (0.34) | KDM4ESMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL25328099 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1SMYD2CYP3A4HTT | |
| SCHEMBL29102862 | 0.71 | SMYD2 (0.38) | ALDH1A1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL1291772 | 0.70 | LMNA (0.42) | ALDH1A1SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL23528479 | 0.70 | SMYD2 (0.36) | KDM4EALDH1A1HSD17B10SMYD2CYP3A4 | |
| SCHEMBL29051719 | 0.70 | LMNA (0.47) | KDM4ESMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL4479571 | 0.70 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL29967957 | 0.70 | SMYD2 (0.36) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |