Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8562935 | 0.91 | CCKBR (0.79) | CCKBR | |
| SCHEMBL8561454 | 0.90 | CCKBR (0.68) | CCKBR | |
| SCHEMBL8648241 | 0.87 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8648018 | 0.84 | CCKBR (0.70) | CCKBR | |
| SCHEMBL8559175 | 0.83 | CCKBR (0.80) | CCKBR | |
| SCHEMBL8563195 | 0.82 | CCKBR (0.84) | CCKBR | |
| SCHEMBL8564471 | 0.80 | CCKBR (0.63) | CCKBR | |
| SCHEMBL8635376 | 0.75 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8651647 | 0.74 | CCKBR (0.85) | CCKBR | |
| SCHEMBL8563447 | 0.74 | KDM1A (0.45) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | claimed |
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | claimed |
| EP-0710230-A1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-05-08 | — | — | EP | claimed |
| WO-1995003285-A1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO SPA (IT) | 1995-02-02 | — | — | WO | claimed |
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | disclosed |
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |
| EP-0710230-A1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO S.p.A. (IT) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003285-A1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO SPA (IT) | 1995-02-02 | — | — | WO | disclosed |