Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653716 | 0.80 | CCKBR (0.45) | CCKBR | |
| SCHEMBL8866387 | 0.78 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8562935 | 0.78 | CCKBR (0.79) | CCKBR | |
| SCHEMBL8564644 | 0.77 | CCKBR (0.49) | KDM1ACCKBRKDM4EMAPT | |
| SCHEMBL8547144 | 0.76 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8561454 | 0.76 | CCKBR (0.68) | CCKBR | |
| SCHEMBL8556701 | 0.75 | CCKBR (0.46) | CCKBR | |
| SCHEMBL8620796 | 0.74 | CCKBR (0.61) | CCKBR | |
| SCHEMBL8866621 | 0.74 | CCKBR (0.64) | CCKBR | |
| SCHEMBL8563090 | 0.74 | CCKBR (0.65) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | disclosed |
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | disclosed |