Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22897819 | 0.67 | TSHR (0.53) | SMN1; SMN2GPR35ALDH1A1MAPTTDP1 | |
| SCHEMBL7011711 | 0.63 | KDM4E (0.35) | ALDH1A1 | |
| SCHEMBL12086376 | 0.61 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL28339878 | 0.61 | BACE1 (0.44) | SMN1; SMN2GPR35ALDH1A1MAPTTSHR | |
| SCHEMBL18314720 | 0.61 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL7009673 | 0.60 | KDM4E (0.40) | SMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL11564941 | 0.60 | ALDH1A1 (0.38) | SMN1; SMN2GPR35ALDH1A1MAPTTDP1 | |
| SCHEMBL1341344 | 0.59 | PDE7A (0.54) | SMN1; SMN2ALDH1A1MAPTTDP1LMNA | |
| SCHEMBL134539 | 0.59 | GPR35 (0.57) | SMN1; SMN2GPR35ALDH1A1MAPTTDP1 | |
| SCHEMBL22389455 | 0.59 | MAPT (0.61) | SMN1; SMN2ALDH1A1MAPTL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843663-A1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-05-27 | — | — | EP | claimed |
| EP-0843663-A1 | 4-ARYL-THIO-PYRIDIN-2(1H)-ONES, DRUGS CONTAINING SAME, AND USES THEREOF FOR TREATING HIV-RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1998-05-27 | — | — | EP | disclosed |