Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563172 | 0.80 | HTR1D (0.53) | HTR1DSCN9ASIGMAR1GAAMAPK1 | |
| SCHEMBL8425551 | 0.79 | GRIN2B (0.50) | SLC6A3SLC6A4SIGMAR1GRIN2DGRIN3B | |
| SCHEMBL8423724 | 0.74 | SMN1; SMN2 (0.39) | HTR1DMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4650718 | 0.73 | TSHR (0.48) | MEN1MAPTKMT2ASMN1; SMN2SLC6A3 | |
| SCHEMBL8424659 | 0.70 | HTR1D (0.38) | HTR1DSCN9ASLC6A3SLC6A4SIGMAR1 | |
| SCHEMBL6043335 | 0.69 | HTR1D (0.76) | HTR1DSIGMAR1GAAMAPK1HTT | |
| SCHEMBL8425479 | 0.68 | SCN9A (0.39) | HTR1DSCN9AMEN1KMT2ASLC6A3 | |
| SCHEMBL8423851 | 0.68 | HTR1D (0.59) | HTR1DSCN9AMEN1MAPTKMT2A | |
| SCHEMBL11868828 | 0.68 | HTR1D (0.60) | HTR1DSIGMAR1GAAMAPK1HTT | |
| SCHEMBL23343753 | 0.67 | OPRL1 (0.65) | SLC6A3SLC6A4GRIN2DGRIN3BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |