Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423851 | 0.86 | HTR1D (0.59) | HTR1DHTTSCN9ASIGMAR1LMNA | |
| SCHEMBL8425616 | 0.83 | HTR1D (0.45) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8563176 | 0.80 | HTR1D (0.46) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8425473 | 0.80 | HTR1D (0.52) | HTR1DGAAMAPK1SIGMAR1LMNA | |
| SCHEMBL8425548 | 0.79 | OPRL1 (0.47) | SIGMAR1 | |
| SCHEMBL8423963 | 0.77 | LMNA (0.46) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL6043335 | 0.76 | HTR1D (0.76) | HTR1DGAAMAPK1HTTNPSR1 | |
| SCHEMBL8422264 | 0.76 | HTR1D (0.57) | HTR1DHTTSCN9ASIGMAR1LMNA | |
| SCHEMBL8424340 | 0.76 | OPRL1 (0.51) | SIGMAR1LMNA | |
| SCHEMBL8425741 | 0.76 | NPSR1 (0.52) | HTR1DGAAMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |