Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423722 | 0.82 | HTR1D (0.41) | SMN1; SMN2NPC1RAB9ATP53LMNA | |
| SCHEMBL8424659 | 0.74 | HTR1D (0.38) | RAB9ALMNASLC6A4SLC6A3HTR1D | |
| SCHEMBL8563176 | 0.74 | HTR1D (0.46) | SMN1; SMN2SLC6A4SLC6A3HTR1DMAPK1 | |
| SCHEMBL8425479 | 0.73 | SCN9A (0.39) | RAB9ASLC6A4SLC6A3HTR1DMAPK1 | |
| SCHEMBL30960368 | 0.69 | GRIN2B (0.44) | HPGDL3MBTL1LMNAPOLBGAA | |
| SCHEMBL8422259 | 0.66 | HTR1D (0.43) | LMNAHTR1DMAPK1GAAHTT | |
| SCHEMBL8422448 | 0.66 | HTR1D (0.43) | LMNAHTR1DMAPK1GAAHTT | |
| SCHEMBL8425741 | 0.66 | NPSR1 (0.52) | LMNAHTR1DMAPK1GAAHTT | |
| SCHEMBL8422132 | 0.66 | HTR1D (0.43) | LMNAHTR1DMAPK1GAAHTT | |
| SCHEMBL8423963 | 0.65 | LMNA (0.46) | LMNAHTR1DMAPK1GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919802-A | Methods of preventing and/or treating temporal lobe epilepsy | PRINCETON UNIVERSITY (US) | 1999-07-06 | — | — | US | disclosed |