Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549909 | 0.87 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7548733 | 0.75 | MAPT (0.54) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7155256 | 0.75 | ALDH1A1 (0.63) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7155399 | 0.75 | NPC1 (0.60) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7153692 | 0.75 | NPC1 (0.48) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7155417 | 0.74 | HDAC1 (0.48) | KDM4EALDH1A1HSD17B10MAPTKMT2A | |
| SCHEMBL8406573 | 0.72 | — | — | |
| SCHEMBL8518780 | 0.72 | NPC1 (0.44) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7153631 | 0.72 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL7156596 | 0.72 | BACE1 (0.38) | KDM4EALDH1A1HSD17B10MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927167-A1 | 2-PHENYL BENZIMIDAZOLE DERIVATIVES AS MCP-1 ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998006703-A1 | 2-PHENYL BENZIMIDAZOLE DERIVATIVES AS MCP-1 ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |