Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.51 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556372 | 0.91 | KCNJ5 (0.51) | AVPR2AVPR1AKCNJ5KCNJ3THRB | |
| SCHEMBL8561770 | 0.91 | AVPR2 (0.47) | AVPR2AVPR1AHSD17B3 | |
| SCHEMBL8560236 | 0.88 | MEN1 (0.48) | AVPR2AVPR1A | |
| SCHEMBL8559196 | 0.85 | THRB (0.55) | KCNJ5KCNJ3THRB | |
| SCHEMBL8561962 | 0.83 | AVPR2 (0.58) | AVPR2AVPR1A | |
| SCHEMBL8556841 | 0.83 | AVPR2 (0.65) | AVPR2AVPR1A | |
| SCHEMBL8562554 | 0.82 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL8559571 | 0.82 | AVPR2 (0.62) | AVPR2AVPR1A | |
| SCHEMBL8558803 | 0.81 | NAMPT (0.57) | AVPR2AVPR1A | |
| SCHEMBL7340964 | 0.81 | KCNJ5 (0.48) | KCNJ5KCNJ3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640592-B1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-12-30 | — | — | EP | disclosed |