Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563381 | 0.84 | HPGD (0.62) | SMN1; SMN2ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL13778192 | 0.82 | RAB9A (0.51) | SMN1; SMN2MAPTLMNAHPGDGAA | |
| SCHEMBL10948798 | 0.81 | SMN1; SMN2 (0.65) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| SCHEMBL8361578 | 0.80 | PTPN1 (0.76) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| SCHEMBL14509053 | 0.79 | POLB (0.61) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| SCHEMBL10952227 | 0.78 | LMNA (0.72) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| Malic Acid SCHEMBL2465724 | 0.77 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL9979382 | 0.77 | POLB (0.63) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| SCHEMBL9979332 | 0.77 | POLB (0.63) | SMN1; SMN2POLBALDH1A1TDP1MAPT | |
| SCHEMBL17368409 | 0.77 | POLB (0.63) | SMN1; SMN2POLBALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517996-B2 | Azole compound | AJINOMOTO CO., INC. (JP) | 2009-04-14 | — | — | US | disclosed |