Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563549 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19CYP1A1CYP1A2 | |
| SCHEMBL7750101 | 0.88 | NPC1 (0.46) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP1B1 | |
| SCHEMBL7750096 | 0.88 | NPC1 (0.46) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP1B1 | |
| SCHEMBL8566374 | 0.87 | USP2 (0.45) | ALDH1A1CYP2C9CYP2C19CYP1A1CYP1A2 | |
| SCHEMBL8566376 | 0.87 | USP2 (0.45) | ALDH1A1CYP2C9CYP2C19CYP1A1CYP1A2 | |
| SCHEMBL7746456 | 0.80 | NPC1 (0.51) | ALDH1A1CYP2C19CYP1A2LMNAKDM4E | |
| SCHEMBL7746460 | 0.80 | NPC1 (0.51) | ALDH1A1CYP2C19CYP1A2LMNAKDM4E | |
| SCHEMBL7749839 | 0.77 | NPC1 (0.50) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP1B1 | |
| SCHEMBL7749846 | 0.77 | NPC1 (0.50) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP1B1 | |
| SCHEMBL7747853 | 0.77 | NPC1 (0.47) | ALDH1A1CYP2C9CYP1A2CYP2D6CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596406-B1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0596406-A1 | Imidazo (1,2-a) Pyridines as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |